|near future the genome of a human embryo could be modified to be the “perfect” baby. I had seen on social media a wle back talking about using stem cell engineering to have a baby outside the womb and I thought it was a joke until now. Ts new discovery will bring a lot of controversy, because women|
Gene therapy has changed since the arrival of , a novel and ghly targeted gene editing tool that no longer requires the use of viral carriers. Combined with cloning, stem cell research and tissue engineering, the day of designer babies is not far away. In fact, it is a reality and we are having to discuss etcs in reproductive medicine anew. The technology in question are grown from stem cells entirely outside a woman’s womb, as explained by Carl Zimmer in the New York Times. John D. Aach and s colleagues explored the etcs of creating what they call “ ” — Sheefs, for short. For now, the most advanced Sheefs are very simple assemblies of cells. Discuss how a combination of the gene editing tool CRISPR and stem cell based synthetic embryo technology will change the way we tnk about reproductive technologies and gene therapy. After reading the first article, I am mind blown. CRISPR–Cas9 is a modern tool that molecular biologists have been using to slice the genome in human cells and alter the genome however they’d like. Ts tool has become very popular because of its potential to treat diseases. Researchers can still working on using the tool to understand cell fate and how to possibly manipulate it. Wch can lead to some amazing results such as “turning off” a gene for a specific disease. The CRISPR-Cas9 can also allow scientists to edit the genes of human embryos! Wch first of all is insanely crazy because there is a possibility that in the near future the genome of a human embryo could be modified to be the “perfect” baby. I had seen on social media a wle back talking about using stem cell engineering to have a baby outside the womb and I thought it was a joke until now. Ts new discovery will bring a lot of controversy, because women will no longer be the only one to carry a cld, wch could stir up a lot of religious beliefs. In the New York Times article, the authors mention how ts could be a discovery with a lot of etcal issues. Ts new technology can change so many tngs in the future, like who gets to decide and regulate access to embryo editing? Will ts been mainly available to gh income people? I tnk it’s an amazing tool but there a lot of etcal guidelines that would need to be set. 1. List the common infertility problems in women. What is the major infertility problem in men? Is it correctable? 2. Why should women consider collecting and freezing oocytes for use later in life when they want to have cldren? What are the risks associated with older women having cldren? 3. In selecting target cells to receive a transferred gene in gene therapy, what factors do you tnk would have to be taken into account? 4. A couple has a cld with neurofibromatosis. They come to your genetic counseling office for help. After taking an extensive family story, you determine that there is no story of ts disease on either side of the family. The couple wants to have another cld and wants to be advised about the risks of that cld having neurofibromatosis. What advice do you give them?