Paper Writing Services (i.e., what is the change in potential from resting)? b) If gI at the peak of the IPSP is 1 milliSiemens, what
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where grest is the leakage current wch maintains the resting potential, Erest is the normal resting potential, gE is the conductance due to excitatory post-synaptic channels (e.g., AMPA channels), ErevE is the reversal potential for the excitatory channels, gI is the conductance due to inbitory post-synaptic channels (e.g., GABA channels) and ErevI is the reversal potential for the |
The membrane potential, Em, of a post-synaptic cell can be calculated from the following equation: equation in attachment where grest is the leakage current wch maintains the resting potential, Erest is the normal resting potential, gE is the conductance due to excitatory post-synaptic channels (e.g., AMPA channels), ErevE is the reversal potential for the excitatory channels, gI is the conductance due to inbitory post-synaptic channels (e.g., GABA channels) and ErevI is the reversal potential for the inbitory channels (ts equation comes from the equivalence circuit discussed in Lecture 13 & 14, slide 21). Assume grest = 1 milliSiemens, Erest = -65 mV, ErevE = -10 mV, ErevI = -70 mV. a) If gE at the peak of the EPSP is 2 milliSiemens, what is the height of the EPSP without an IPSP (i.e., what is the change in potential from resting)? b) If gI at the peak of the IPSP is 1 milliSiemens, what is the change in potential from resting? c) What is the sum of the peak IPSP voltage change and the peak EPSP voltage change?
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