Must post first.Must post first. Minimum 400 word count. is the pathophysiology of opioid addiction? Why is it so difficult to overcome the opioid addiction? do opioids do to your

Must post first.Must post first. Minimum 400 word count.  is the pathophysiology of opioid addiction? Why is it so difficult to overcome the opioid addiction? do opioids do to your brain? is withdrawal? is opioid tolerance?Explain in detail the use of naloxone (narcan) for reversal of respiratory distress thought to be overdose related and describe the Safety issues with use of personal protective equipment for healthcare professionals/first responders. How does one obtain naloxone (narcan)? are the side effects? How is it administered? How long is the duration of effect or length of action?  May it be administered more than once? happens when it is administered? results do you expect to see? problems or pitfalls do you see, if any? insurance changes have happened to combat overdose deaths? Follow the grading rubric for discussion boards, .  Use APA style for citations and references for literature support of current knowledge and practice. Posta 100 word count, robust, respectful replies to 2 course mates with a reference for each one. May have been used in Initial Post but it deserves its own citation and reference again. You must start a thread before you can read and reply to other threads

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